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AgeXtend - AI-Powered Solution for Anti-Aging Research
AgeXtend - AI-Powered Solution for Anti-Aging Research
13-12-2024
- In December 2024, IIIT-Delhi researchers have developed AgeXtend as a tool to efficiently cut down the time taken to identify viable molecules with geroprotectors (anti-aging properties) than conventional research.
- They have used Artificial Intelligence (AI) to predict and identify compounds with anti-aging properties.
- Over a span of two years, the team screened more than 1.1 billion compounds and highlighted several promising molecules that showed potential for anti-ageing effects.
- Scanning 1.2 billion molecules makes this the largest study in the field of anti-aging research.
- Scanned compounds included commercial drugs, Chinese drugs, ayurveda and molecules approved by the U.S. Food and Drug Administration.
- These molecules were tested and validated through experiments on yeast, worms (C. elegans), and human cell models. Less than 1% of the identified compounds demonstrated anti-ageing properties.
- It assesses their safety and analyses their biological effects. By studying the structure of new molecules, AgeXtend can predict with high accuracy whether they possess geroprotective qualities.
- Unique Approach of AgeXtend: Unlike other research tools, AgeXtend not only identifies potential anti-aging compounds but also provides explanations for its choices.
a. It reveals the underlying mechanisms behind the selection of these compounds, offering valuable insights that can guide future research and help pinpoint areas that need further validation. - Working: AgeXtend successfully identified the benefits of well-known molecules like metformin and taurine, even without prior knowledge of these compounds.
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